Myrtle Beach is a resort city on the East Coast of the United States in Horry County, South Carolina. It is located in the center of a long an…Myrtle Beach is a resort city on the East Coast of the United States in Horry County, South Carolina. It is located in the center of a long and continuous 60-mile stretch of beach known as the "Grand Strand” in the northeastern part of the state. Its year-round population was 35,682 as of the 2020 census, making it the 13th-most populous city in South Carolina.