BCR-ABL1 is an abnormal gene present in certain types of leukemia. Genetic testing for BCR-ABL1 helps doctors diagnose these cancers and assess their response to treatment. If you or someone you ...

Each chromosome pair viewed in a karyotype appears to have its own distinct "bar code" of bands. What changes do scientists look for in a karyotype when diagnosing diseases and disorders?

Expert Rev Mol Diagn. 2013;13(6):601-611. In other situations, normal microarray analysis in the presence of an abnormal karyotype, such as marker chromosomes, is reassuring, as it indicates that ...

DNA (deoxyribonucleic acid) is a double-stranded molecule that contains all the genetic information about you as an ...

Translocations generate novel chromosomes, but are often linked to disorders like infertility and cancer. How do these new chromosomes generate problems, and how are they detected? Translocations ...