An R75W mutation in the gap junction β2 (GJB2) gene causes severe fragmentation of gap junction plaques, connecting adjacent ...

Sickle-cell anemia is due to a mutation in the gene encoding the β-subunit of hemoglobin (called HBB), which leads to an abnormal structure of the β-subunit protein chain and the sickle-cell ...

Zynext Ventures is investing in Illexcor Therapeutics to advance the clinical development of ILX002, its lead candidate for ...

Sickle Cell Disease is a complex and debilitating genetic blood disorder that primarily affects people of African, Mediterranean, Middle Eastern, and Indian ancestry. It is caused by a mutation in ...

It is caused by a mutation in the hemoglobin gene (HBB). CRISPR-Cas9 acts as molecular scissors that can precisely snip out parts of the HBB genome in living cells. To remedy sickle cells ...

View Full Profile. Learn about our Editorial Policies. Today, the cause of sickle cell disease is well understood to be a point mutation in a hemoglobin gene called HBB that makes red blood cells grow ...