CREST syndrome, or limited systemic sclerosis, is a rare autoimmune disease that causes changes and scarring of the body's blood vessels and connective tissues. The acronym CREST stands for the main ...

Delayed esophageal transit on scintigraphy among patients with SSc is linked to a more severe disease phenotype.

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed ...

Nkarta is laying off a third of its employees, including half of the biotech’s executive leadership, as the company diverts ...

Two new studies led by researchers at the Hospital for Special Surgery (HSS) have uncovered key biological mechanisms driving systemic sclerosis (SSc), or scleroderma – a rare and often devastating ...

Acute and chronic renal diseases remain common complications of systemic sclerosis. Although treatment for acute scleroderma renal crisis may arrest the rapid progression of renal disease ...

Having established success in cancer, biopharma is now looking to leverage CAR T therapies against a new target, autoimmune ...

New research explores the potential of adipose-derived stem cells to reduce fibrosis and modulate the immune system in ...

Using mice, lab-grown cells and clues from a related disorder, Johns Hopkins researchers have greatly increased understanding of the causes of systemic sclerosis, showing that a critical culprit ...