Jamie-Lynn Sigler and Robert Iler, who played siblings Meadow and A.J. Soprano, respectively, face off in PEOPLE's exclusive ...

Jamie-Lynn Sigler is going up against her Sopranos brother, Robert Iler, on The $100,000 Pyramid! In PEOPLE's exclusive look at the March 23 episode of the game show, the two former costars ...

Christina Applegate is shedding more light on her battle with multiple sclerosis. “For three years, since I was diagnosed, ...

Christina Applegate shared that she thinks her gastrointestinal symptoms are related to multiple sclerosis, explaining, "I ...

Applegate's podcast cohost Jamie-Lynn Sigler informed the actress that vomiting and having diarrhea simultaneously is called ...

Christina Applegate is letting fans in on some of the details of her struggle against MS over the past three years.

They’ve done every test known to man on me, put so much radiation into my body from CT scans to everything else,” the actress ...

Since she was diagnosed with multiple sclerosis in 2021, Christina Applegate hasn't shied away from sharing the oftentimes ...

Pawn Stars personality Rick Harrison is reflecting on the death of his son, Adam, at the age of 39. Adam died from a fentanyl ...

"I get all the pain" from bowel movements Matt Winkelmeyer/Getty Christina Applegate and Jamie-Lynn Sigler shared listener emails on the one-year anniversary of their podcast about MS, MesSy After ...

Christina Applegate revealed in a new episode of her podcast that she has been hospitalized "upwards of 30 times" due to MS ...