Jamie-Lynn Sigler and Robert Iler, who played siblings Meadow and A.J. Soprano, respectively, face off in PEOPLE's exclusive ...

Jamie-Lynn Sigler is going up against her Sopranos brother, Robert Iler, on The $100,000 Pyramid! In PEOPLE's exclusive look at the March 23 episode of the game show, the two former costars ...

The Sopranos' actress says her own experience coping with MS has helped with her 11-year-old son's remarkable recovery from a rare autoimmune condition Cristina Fisher Jamie-Lynn Sigler's 11-year ...

Jamie-Lynn Sigler is reflecting on the scariest time in her life when her 11-year-old son Beau was hospitalized with a life-threatening autoimmune condition last summer. “Those were the hardest ...

Christina Applegate is shedding more light on her battle with multiple sclerosis. “For three years, since I was diagnosed, ...

Sagal appeared on the March 11 episode of Christina Applegate and Jamie-Lynn Sigler's 'MeSsy' podcast, where she shared how ...

Applegate's podcast cohost Jamie-Lynn Sigler informed the actress that vomiting and having diarrhea simultaneously is called ...

Jamie-Lynn Sigler has faced her own battles with multiple sclerosis, but nothing prepared her for the terrifying ordeal she endured last summer when her 11-year-old son, Beau, was hospitalized with a ...

Christina Applegate is letting fans in on some of the details of her struggle against MS over the past three years.

Some seven months after her son Beau was hospitalized for 33 days with a rare autoimmune condition, Jamie-Lynn Sigler is now sharing some of the harrowing details of his fight for life.

Jamie-Lynn Sigler's 11-year-old son Beau was hospitalized for 33 days with a rare autoimmune condition known as acute disseminated encephalomyelitis Sigler says her experience living with MS helped ...