The No. 2 seed Alabama Crimson Tide and the No. 7 seed Saint Mary's Gaels square off in a second-round showdown on Sunday in the 2025 NCAA Tournament. The Crimson Tide knocked off Robert Morris 90-81 in the first round.

Madness NCAA Tournament second-round game betting odds, point spreads, moneylines, over/unders, totals for Saturday, Sunday. Who is favored?

Today concludes the opening weekend of the NCAA Tournament, with the other half of the bracket looking to punch their tickets to the Sweet 16 — and extend their March Madness odds for a few more days. We've got the latest odds for today's Second Round games, including some high-profile matchups and Cinderellas looking to reach the Sweet 16.