Not long after the first flu shot was introduced in 1945 by University of Michigan virologist Thomas Francis and his ...

Older adults who were exposed to seasonal flu viruses that circulated prior to 1968 are more likely to have some protection ...

H5N1 influenza is evolving rapidly, weakening the effectiveness of existing antibodies and increasing its potential threat to ...

The H5N1 avian influenza virus is mutating to evade immune defenses in mammals following prior infection or vaccination.

New research suggests that past exposure to seasonal flu viruses may help protect people from severe illness caused by the ...

Findings show potential for new lipid-based delivery formulations as a platform technology for immunizationPhiladelphia, PA, ...

Early flu exposure helps immunity against H5N1 infection, with older adults having stronger antibody responses.

New computational modeling of avian influenza variants’ immunoprotein interactions – developed by a research team at the University of North Carolina at Charlotte – reveals the H5N1 influenza virus is ...

Currently, human influenza vaccines use Hemagglutinin—a protein on the surface of the virus that is denoted by the "H" in the virus name—to train our immune system to recognize the flu.

To maintain vaccine efficacy, WHO regularly updates influenza vaccine strains based on global epidemiological, virological, ...

Because influenza evolves rapidly, it hasn't been possible to target any highly conserved genes; instead, it targets the hemagglutinin – the 'H' in flu viruses such as H5N1 – which is a ...