A tractor-trailer crash shut down a stretch of Interstate 81 in Franklin County, according to PennDOT. Video above: Headlines ...

A two-vehicle crash late Tuesday morning caused significant traffic delays on Interstate 81 near mile marker 305.9 in Frederick County, south of Stephens City.

Kara M. Webber, of Williamsport, was pronounced dead Sunday after a crash on I-81 in W.Va. Police found Webber crossed median ...

INWOOD, W.Va. — A crash that killed a Maryland woman and shut down I-81 in Berkeley County remains under investigation. The ...

The New York State Department of Transportation is alerting drivers to upcoming lane reductions on I-81 Northbound and Southbound in Syracuse.The lane reduction ...

The New York State Department of Transportation is alerting drivers of lane closures along Interstate 81 starting Tuesday, ...