Jamie-Lynn Sigler and Robert Iler, who played siblings Meadow and A.J. Soprano, respectively, face off in PEOPLE's exclusive ...

Christina Applegate and Jamie-Lynn Sigler share painful MS experiences on MesSy podcast, offering support and advice for ...

Sagal appeared on the March 11 episode of Christina Applegate and Jamie-Lynn Sigler's 'MeSsy' podcast, where she shared how she started drinking at 15 to self-medicate and to avoid dealing with her ...

Christina Applegate shared that she thinks her gastrointestinal symptoms are related to multiple sclerosis, explaining, "I get all the pain" from bowel movements.

Christina Applegate is shedding more light on her battle with multiple sclerosis. “For three years, since I was diagnosed, I’ve been in the hospital upwards of 30 times from throwing up and ...

The former TODAY co-anchor shares the podcasts she loves, plus what to expect from the new season of “Making Space.” ...

They’ve done every test known to man on me, put so much radiation into my body from CT scans to everything else,” the actress revealed on her MeSsy podcast ...

The "Making Space" host also opens up about what she hopes her daughters will one day take away from listening to her podcast ...

"Kelly, I want to address your throwing up and your diarrhea," the Dead to Me actress said on Tuesday's episode of her MeSsy podcast with Jamie-Lynn Sigler. Applegate began to divulge details of ...