Background Previous natural history studies highlighted a consistent heterogeneity of disability trajectories among ...

Apathy is increasingly recognised as a common behavioural syndrome in psychiatric disorders, but it is conceptually ill defined. The aim of this study was to examine the concept of apathy as it is ...

Dr JL Iddon, Department of Academic Neurosurgery, Box 167, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 5RG, UK email jo.iddon{at}cenes.co.uk OBJECTIVES Eleven patients ...

A preregistered systematic review of poststroke psychosis examining clinical characteristics, prevalence, diagnostic procedures, lesion location, treatments, risk factors and outcome. Neuropsychiatric ...

Correspondence to Dr Ruth Ann Marrie, Internal Medicine, University of Manitoba College of Medicine, Winnipeg, MB R3A 1R9, Canada; rmarrie{at}hsc.mb.ca Pain can be one of the worst symptoms of ...

Dr Irene Litvan, Federal Building, Room 714, National Institutes of Health, Bethesda, Maryland 20892, USA. OBJECTIVE To analyse the natural history and survival of corticobasal degeneration by ...

Objective APOE is a strong risk factor for Alzheimer’s disease (AD) and associated with higher low-density lipoprotein cholesterol (LDL-C) levels. Moreover, LDL-C is associated with the development of ...

Seizure-related cardiac arrhythmias are frequently reported and have been implicated as potential pathomechanisms of Sudden Unexpected Death in Epilepsy (SUDEP). We attempted to identify clinical ...

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Background At least 60% of stroke, 40% of dementia and 35% of late-life depression (LLD) are attributable to modifiable risk ...

Dr Paul T Francis, Dementia Research Laboratory, Division of Biomolecular Sciences, Guy’s, King’s and St Thomas’ Schools of Biomedical Sciences, King’s College, St Thomas Street, London SE1 9RT, UK.

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