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British Journal of Ophthalmology is pleased to present a topic collection on Generative AI in Ophthalmology. The field of ophthalmology has witnessed remarkable advancements in recent years, and the emergence of generative artificial intelligence (AI) techniques has further revolutionized research and clinical applications.

Clinical science: Age–period–cohort analysis of the global burden of visual impairment according to major causes: an analysis of the Global Burden of Disease Study 2019 (25 April, 2024)

Foundation models represent a paradigm shift in artificial intelligence (AI), evolving from narrow models designed for specific tasks to versatile, generalisable models adaptable to a myriad of diverse applications. Ophthalmology as a specialty has the potential to act as an exemplar for other medical specialties, offering a blueprint for integrating foundation models …

The British Journal of Ophthalmology (BJO) is an international peer-reviewed journal for ophthalmologists and visual science specialists. BJO publishes clinical investigations, clinical observations, and clinically relevant laboratory investigations related to ophthalmology.

Glossary 5-FU 5-fluorouracil. AAC Acute angle closure. ACG Angle closure glaucoma. AGIS Advanced glaucoma intervention study. AH Aqueous humour. AI Artificial intelligence. ALT Argon laser trabeculoplasty. BAC Benzalkalonium chloride. CCT Central corneal thickness. CDR Cup to disc ratio. CIGTS Initial glaucoma treatment study. CNTGS Collaborative normal tension glaucoma study. DCT Dynamic ...

Aims To compare and rank the myopia control effects of different light wavelengths in children using a systematic review and Bayesian network meta-analysis (Bayesian NMA). Methods The review protocol was registered with PROSPERO. We searched PubMed, EMBASE and MEDLINE for relevant clinical and animal studies published as of 2 February 2023. We included studies comparing red, violet or full ...

Background/aims Quantity of cataract surgery has long been an important public health indicator to assess health accessibility, however the quality of care has been less investigated. We aimed to summarise the up-to-date evidences to assess the real-world visual outcomes after cataract surgery in different settings. Methods A systematic review was undertaken in October 2021. Population-based ...

Macular dystrophies (MDs) consist of a heterogeneous group of disorders that are characterised by bilateral symmetrical central visual loss. Advances in genetic testing over the last decade have led to improved knowledge of the underlying molecular basis. The developments in high-resolution multimodal retinal imaging have also transformed our ability to make accurate and more timely diagnoses ...

Background Ocular toxoplasmosis is common across all regions of the world. Understanding of the epidemiology and approach to diagnosis and treatment have evolved recently. In November 2020, an international group of uveitis-specialised ophthalmologists formed the International Ocular Toxoplasmosis Study Group to define current practice. Methods 192 Study Group members from 48 countries ...